PHYSIOLOGICAL BASIS OF HYBRID VIGOR AND RESILIENCE
Understanding the genetic and physiological bases of complex traits that are important in shellfish aquaculture has been a long-standing goal of ours. Hedgecock has had a long-standing collaboration with Professor Donal Manahan of the University of Southern California to research the genetic and physiological basis of hybrid vigor and resilience to environmental stress. A thorough understanding of basic mechanism could enable the development of biomarkers capable of predicting, during very early life-stages, the performance of shellfish stocks in the field. Such biomarkers would greatly increase the efficiency of genetic improvement.
Bayne, B. L., D. Hedgecock, D. McGoldrick, and R. Rees. 1999. Feeding behavior and metabolic efficiency contribute to growth heterosis in Pacific oysters [Crassostrea gigas (Thunberg)]. Journal of Experimental Marine Biology and Ecology 233:115-130.
Frieder, C.A., S.L. Applebaum, T.-C. Francis Pan, D. Hedgecock and D. T. Manahan. 2017. Metabolic costs of calcification in bivalve larvae under experimental ocean acidification. ICES Journal of Marine Science 74: 941-954.
Physiological bases of genetically determined variation in growth of marine invertebrate larvae: A study of growth heterosis in the bivalve Crassostrea gigas
Pace, D. A., A. G. Marsh, P. Leong, A. Green, D. Hedgecock, and D. T. Manahan. 2006. Physiological bases of genetically determined variation in growth of marine invertebrate larvae: A study of growth heterosis in the bivalve Crassostrea gigas. Journal of Experimental Marine Biology and Ecology 335:188-209.
Applebaum, S.L., T.-C.F. Pan, D. Hedgecock and D.T. Manahan. 2014. Separating the nature and nurture of energy allocation in response to global change. Integrative and Comparative Biology 54:284-295.