Hubert, S., E. Cognard, and D. Hedgecock. 2009. Centromere-mapping in triploid families of the Pacific oyster Crassostrea gigas (Thunberg). Aquaculture 288:172–183.

This paper helped to improve the genetic linkage map for the Pacific oyster and aided subsequent efforts to map genes underlying traits of commercial importance, such as hybrid vigor, sex determination, and survival. This research was supported by grants from the National Sea Grant College Program and the National Science Foundation.

Ghiselli, F., L. Milani, P. L. Chang, D. Hedgecock, J. P. Davis, S. V. Nuzhdin, and M. Passamonti. 2012. De novo assembly of the Manila clam Ruditapes philippinarum transcriptome provides new insights into expression bias, mitochondrial doubly uniparental inheritance and sex determination. Molecular Biology and Evolution 29: 771-786.

Zhang, G., X. Fang, X. Guo, L. Li, R. Luo, F. Xu, P. Yang, L. Zhang, X. Wang, H. Qi, Z. Xiong, H. Que, Y. Xie, P. W. H. Holland, J. Paps, Y. Zhu, F. Wu, Y. Chen, J. Wang, C. Peng, J. Meng, L. Yang, J. Liu, B. Wen, N. Zhang, Z. Huang, Q. Zhu, Y. Feng, A. Mount, D. Hedgecock, Z. Xu, Y. Liu, T. Domazet-Lošo, Y. Du, X. Sun, S. Zhang, B. Liu, P. Cheng, X. Jiang, J. Li, D. Fan, W. Wang, W. Fu, T. Wang, B. Wang, J. Zhang, Z. Peng, Y. Li, N. Li, J. Wang, M. Chen, Y. He, F. Tan, X. Song, Q. Zheng, R. Huang, H. Yang, X. Du, L. Chen, M. Yang, P. M. Gaffney, S. Wang, L. Luo, Z. She, Y. Ming, W. Huang, S. Zhang, B. Huang, Y. Zhang, T. Qu, P. Ni, G. Miao, J. Wang, Q. Wang, C. E. W. Steinberg, H. Wang, N. Li, L. Qian, G. Zhang, X. Liu, Y. Li, Y. Yin, and J. Wang. 2012. The oyster genome reveals stress adaptation and complexity of shell formation. Nature 490:49-52 (4 October 2012).

This is the publication of the genome sequence of the Pacific oyster. Hedgecock and Davis supplied the fourth-generation inbred oyster whose genome was sequenced. Hedgecock, a co-author, confirmed the pedigree of the oyster, using genetic markers, and provided advice on the overall project, the rationale for which was established by Hedgecock et al (2005, below). The development of this inbred line was made possible by grants from the USDA.

Hedgecock, D., G. Shin, A.Y. Gracey, D. Van Den Berg and M.P. Samanta. 2015. Second-generation linkage maps for the Pacific oyster Crassostrea gigas reveal errors in assembly of genome scaffolds. G3: Genes Genomes Genetics 5: 2007-2019.

A continuation of a decade-long effort to construct genetic linkage maps for the Pacific oyster, this paper not only provided a consensus, high-density genetic map but also provided definitive evidence that the genome assembly provided by Zhang et al (2012, below) has many errors that need to be corrected.

Sun, X.J., G. Shin, and D. Hedgecock. 2015. Inheritance of high-resolution melting profiles in assays targeting single nucleotide polymorphisms in protein-coding sequences of the Pacific oyster Crassostrea gigas: Implications for parentage assignment of experimental and commercial broodstocks. Aquaculture 437: 127-139.