Fixation, segregation and linkage of allozyme loci in inbred families of the Pacific oyster Crassostrea gigas (Thunberg):

McGoldrick, D. J., and D. Hedgecock. 1997. Fixation, segregation and linkage of allozyme loci in inbred families of the Pacific oyster Crassostrea gigas (Thunberg): Implications for the causes of inbreeding depression. Genetics 146:321-334.

Continue ReadingFixation, segregation and linkage of allozyme loci in inbred families of the Pacific oyster Crassostrea gigas (Thunberg):

Quantitative Trait Locus Analysis of stage-specific inbreeding depression in the Pacific oyster Crassostrea gigas

Plough, L. V., and D. Hedgecock. 2011. Genome-wide analysis of stage-specific inbreeding depression in the Pacific oyster Crassostrea gigas. Genetics 189:1-14.

This paper, drawn from Louis Plough’s Ph.D. dissertation, provides dramatic documentation for a large number of highly deleterious mutations in the Pacific oyster. These mutations are expressed during the larval stages, particularly during metamorphosis, resulting in genotype-dependent mortality that amounts to ~96% of starting numbers (fertilized eggs). This research was supported by a grant from the NSF.

Continue ReadingQuantitative Trait Locus Analysis of stage-specific inbreeding depression in the Pacific oyster Crassostrea gigas

Genetic inviability is a major driver of type III survivorship in experimental families of a highly fecund marine bivalve

Plough, L.V., G. Shin and D. Hedgecock. 2016. Genetic inviability is a major driver of type III survivorship in experimental families of a highly fecund marine bivalve. Molecular Ecology 25: 895-910.

Continue ReadingGenetic inviability is a major driver of type III survivorship in experimental families of a highly fecund marine bivalve